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One study found that direct recombinant IGF-1 LR3 administration at days 2, 5, and 7 accelerated muscle healing in mice with strain-injured muscles [1]

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J Clin Med 8:1135

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2 Cryogenic electron microscopy (CEM) imaging demonstrates that orforglipron binds within the upper helical bundle of GLP-1R and acts as a highly potent partial agonist that favors cyclic adenosine monophosphate (cAMP) signaling over beta-arrestin recruitment